Fibromyalgia : about mechanism

Session 1 : What can be said and what kind of research has to be developed about central sensitization as one of the mechanism in FM?

Mechanisms Underlying Pain Amplification in Fibromyalgia Syndrome and Related Somatoform Disorders

• Introduction »
• Evidence for a state of pain amplification in TMD and FMS »
• Putative mechanisms supporting pain amplification in patients with FMS and TMD »
• Peripheral factors »
• Spinal transmission »
• Impaired DNIC »
• Impaired baroreceptor and vagal afferent function »
• Putative genetic factors associated with pain amplification »
• Conclusion »
• Acknowledgements »
• Reference List »

Neuroimaging Contribution to Fibromyalgia Pathophysiology

• Introduction »
• Functional Neuroimaging Methods »
• Functional Neuroimaging of Experimental Pain »
• Functional Neuroimaging in Fibromyalgia »
• Conclusions »

Spinal cord hypersensitivity in FM and other chronic musculoskeletal pain conditions

• Introduction »
• Conclusion »

Pharmacology of Antidepressants in Chronic Pain and Fibromyalgia: Mechanism of Action

• Antidepressants »
• Serotonin and noradrenaline »
• Tryptophan hydroxylase »
• In addition to pain »
• Conclusions »
• Reference List »